PurXcel: The Power of Synergistic Antioxidants
The world is now entirely awake to the health risks associated with low or depleted antioxidant levels. Ideally, we would all be very active outdoors in fresh air and sunshine, eating yummy foods freshly grown from the Earth in excellent soils. Sadly, repeated abuses to our immune systems and poor lifestyle decisions have placed most at risk for long-term chronic conditions.
PURE’s proprietary blend of antioxidants combines ingredients that help improve and modulate the body’s ability to generate its own antioxidants. Each one of the chosen ingredients is amazing by itself, but when combined they provide formidable pressure against harmful free radicals that can damage cells in the body. Here’s a quick run-down of PurXcel’s ingredient and the health benefits they are known to exert in the body. (Each benefit has a related professional health journal citation in the endnotes.)
L-glutathione
L-glutathione is a potent antioxidant that plays a crucial role in cellular detoxification, protecting cells from oxidative stress and helping regenerate other antioxidants, such as vitamins C and E. It also boosts the immune system, aiding in the body’s defense against infections. Studies have shown its ability to improve liver health, particularly by helping detoxify harmful substances. Glutathione can also promote skin health by reducing oxidative damage from UV rays, which can minimize the appearance of wrinkles and support overall skin rejuvenation. Research by Wu et al. highlights glutathione’s critical role in metabolism and antioxidant function, while Pizzorno discusses its benefits in integrative health settings¹².
NAC (N-acetyl L-cysteine)
N-acetyl L-cysteine (NAC) serves as a precursor to glutathione and has strong antioxidant properties that aid in liver detoxification. It is widely used in treating chronic respiratory conditions, as it helps thin mucus, making it easier for patients to breathe. Additionally, NAC has neuroprotective qualities, as it supports neurotransmitter stabilization and prevents oxidative damage in the brain, which is beneficial in managing conditions like Parkinson’s and Alzheimer’s diseases. Studies by Aldini et al. and Deepmala et al. demonstrate its effectiveness in reducing oxidative stress and its neuroprotective benefits³ ⁴.
Aloe Vera
Aloe vera, particularly in the form of BiAloe®, is well known for its anti-inflammatory and soothing properties, making it a popular remedy for gastrointestinal issues such as irritable bowel syndrome (IBS). Its polysaccharides help soothe the digestive tract while its antioxidant-rich composition supports immune function and skin health by promoting hydration and elasticity. Aloe’s role in enhancing overall digestive and skin health is well-supported by research conducted by Surjushe et al. and a systematic review by Vogler and Ernst ⁵ ⁶.
ALA (Alpha-lipoic acid)
Alpha-lipoic acid (ALA) is another antioxidant that plays an important role in energy metabolism by enhancing mitochondrial function, which helps reduce fatigue and improve overall energy levels. ALA also has anti-inflammatory effects and is shown to enhance insulin sensitivity, offering support for people with diabetes by helping regulate blood sugar levels. Furthermore, it has been found to regenerate other antioxidants, thereby protecting against oxidative damage. Shay et al. highlight ALA’s therapeutic potential, while Gomes et al. detail its benefits for managing diabetes ⁷ ⁸.
Moringa Oleifera
Moringa oleifera, often referred to as the “miracle tree,” is rich in essential nutrients and antioxidants. Its anti-inflammatory properties help manage conditions like arthritis, and it has been shown to improve cardiovascular health by lowering cholesterol levels. Additionally, its rich antioxidant profile protects the brain from oxidative stress, potentially improving cognitive function. Leone et al. detail its effects on blood sugar and lipid levels, while Vergara-Jimenez et al. review its bioactive compounds that protect against chronic disease ⁹ ¹⁰. [Learn more about Moringa]
Turmeric
Turmeric, particularly its active component curcumin, is widely recognized for its potent anti-inflammatory and antioxidant effects. It has been shown to reduce joint pain in conditions like arthritis, support brain health by increasing brain-derived neurotrophic factor (BDNF), and promote cardiovascular health by improving the function of the endothelium, which lines blood vessels. The therapeutic roles of curcumin are explored in studies by Gupta et al., and its broader effects on human health are reviewed by Hewlings and Kalman ¹¹ ¹².
Sulphoraphane
Sulforaphane, a compound found in broccoli sprouts, is known for its strong detoxifying properties. It enhances the body’s ability to neutralize carcinogens, supporting cancer prevention efforts. Sulforaphane also exhibits anti-inflammatory benefits and has been studied for its potential in neuroprotection, particularly in conditions like Alzheimer’s disease. Groundbreaking studies by Zhang et al. and Fahey et al. have highlighted its protective effects against chemical carcinogens and its role in cellular detoxification ¹³ ¹⁴. [Brief video about Organic sulfur health benefits]
Superoxide dismutase (SOD)
Superoxide dismutase (SOD), particularly in its Extramel® form, is an essential enzyme that neutralizes harmful superoxide radicals, thereby reducing oxidative stress and inflammation. By lowering oxidative damage, SOD can slow down the aging process, particularly in skin cells, promoting healthier, more youthful-looking skin. Its importance in managing oxidative stress and inflammation is underscored in research by Fattman et al. and Zelko et al., who explore the broad biological implications of SOD activity ¹⁵ ¹⁶.
Cordyceps Sinensis
Cordyceps sinensis is a medicinal fungus known for boosting energy levels and endurance by increasing ATP production, which is particularly beneficial for athletic performance. It also improves respiratory health by enhancing oxygen uptake and utilization. Additionally, Cordyceps has immunomodulatory effects, helping to regulate immune system activity and reduce inflammation. Research by Holliday et al. and Koh et al. supports its efficacy in enhancing stamina and immune function ¹⁷ ¹⁸.
Milk Thistle, or Silybum marianum, is best known for its liver-protective effects, as it helps promote liver cell regeneration and detoxification. It has also been shown to exhibit anti-inflammatory and antioxidant properties, supporting cardiovascular health by reducing LDL cholesterol and stabilizing blood sugar levels. Studies by Flora et al. and Post-White et al. provide substantial evidence for its efficacy in managing liver-related health issues and promoting overall wellness ¹⁹ ²⁰. [Cordyceps also available in Pure Cafe coffee]
These ingredients, as included in PurXcel, offer a comprehensive range of health benefits, supporting detoxification, reducing inflammation, enhancing energy and cognitive function, and protecting against oxidative stress, ultimately promoting overall cellular health and well-being.
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More Info: Frequently Asked Questions (FAQs) PDF
¹ Wu, G. et al. “Glutathione metabolism and its implications for health.” Journal of Nutrition and Biochemistry, 2004.
² Pizzorno, J. “Glutathione! The Great Protector.” Integrative Medicine, 2014.
³ Aldini, G. et al. “N-acetylcysteine as an antioxidant and disulphide breaking agent.” Biochimica et Biophysica Acta (BBA) – General Subjects, 2018.
⁴ Deepmala et al. “N-Acetyl Cysteine in Psychiatry: Current Therapeutic Evidence and Future Directions.” Oxford Academic Journal, 2015.
⁵ Surjushe, A. et al. “Aloe vera: A short review.” Indian Journal of Dermatology, 2008.
⁶ Vogler, B. and Ernst, E. “Aloe vera: A systematic review of its clinical effectiveness.” British Journal of General Practice, 1999.
⁷ Shay, K. et al. “Alpha-lipoic acid as a dietary supplement: Molecular mechanisms and therapeutic potential.” Biochimica et Biophysica Acta, 2009.
⁸ Gomes, M.B. et al. “Effect of alpha-lipoic acid in diabetes: A comprehensive review.” Diabetes and Metabolism Journal, 2012.
⁹ Leone, A. et al. “Moringa oleifera seeds and oil: characteristics and uses for human health.” International Journal of Molecular Sciences, 2015.
¹⁰ Vergara-Jimenez, M. et al. “Nutritional and therapeutic uses of Moringa oleifera leaves in human health: A review.” Current Nutrition Reports, 2017.
¹¹ Gupta, S.C. et al. “Multitargeting by curcumin as revealed by molecular interaction studies.” Natural Product Reports, 2011.
¹² Hewlings, S.J. and Kalman, D.S. “Curcumin: A Review of Its Effects on Human Health.” Foods, 2017.
¹³ Zhang, Y. et al. “A major inducer of anticarcinogenic protective enzymes from broccoli: isolation and elucidation of structure.” Proceedings of the National Academy of Sciences, 1992.
¹⁴ Fahey, J.W. et al. “Broccoli sprouts: An exceptionally rich source of inducers of enzymes that protect against chemical carcinogens.” Proceedings of the National Academy of Sciences, 1997.
¹⁵ Fattman, C.L. et al. “Extracellular superoxide dismutase in biology and medicine.” Free Radical Biology and Medicine, 2003.
¹⁶ Zelko, I.N. et al. “Superoxide dismutase multigene family: A comparison of the CuZn-SOD (SOD1), Mn-SOD (SOD2), and EC-SOD (SOD3) gene structures, evolution, and expression.” Free Radical Biology and Medicine, 2002.
¹⁷ Holliday, J. et al. “Modern Uses of Medicinal Mushrooms.” International Journal of Medicinal Mushrooms, 2004.
¹⁸ Koh, J.H. et al. “Antifatigue and Antioxidant Effects of Cordyceps sinensis Extract in Mice.” Journal of Pharmacological Sciences, 2003.
¹⁹ Flora, K. et al. “Milk Thistle (Silybum marianum) for the therapy of liver disease.” American Journal of Gastroenterology, 1998.
²⁰ Post-White, J. et al. “Milk thistle: effects on liver disease and cirrhosis and clinical adverse effects.” Integrative Cancer Therapies, 2007.
